Profile

Business Description

VistaGen Therapeutics (NASDAQ: VTGN) is a clinical-stage biopharmaceutical company focused on developing new generation therapies for depression and other central nervous system (CNS) disorders. VistaGen’s lead CNS product candidate, AV-101, is an orally available prodrug in Phase 2 development, initially for the adjunctive treatment of major depressive disorder (MDD) in patients with inadequate response to standard FDA-approved antidepressants. AV-101 has the potential to be faster-acting and safer than standard FDA-approved antidepressants, as well as atypical antipsychotics commonly used adjunctively to augment them. AV-101 is a NMDA receptor glycine-binding (Glyв) site antagonist and has been shown in published preclinical studies to provide fast-acting, ketamine-like, antidepressant effects without serious CNS side effects typically associated with ketamine and FDA-approved drug therapies for depression.

AV-101 is being evaluated in an ongoing Phase 2a monotherapy study in MDD, a study being conducted at the U.S. National Institute of Mental Health (NIMH) and being funded by the NIMH, and expected to conclude by the end of 2017. VistaGen is also preparing to launch a Phase 2b study of AV-101 in the first half of 2017 for the adjunctive treatment of MDD.

Company Info

Address:
343 Allerton Avenue
South San Francisco, CA 94080

Telephone:
(650) 577-3600

Fax:
(888) 482-2602

Industry Classifications

Sector:
Healthcare

Industry:
Biotechnology

NAICS:
Pharmaceutical Preparation Manufacturing (325412)

SIC:
Pharmaceutical Preparations (2834)